RNAdesign
Version 0.1.0.0 revision 0 uploaded by ChristianHoener.
Package meta
- Synopsis
- Multi-target RNA sequence design
- Description
The RNA sequence design problem asks for a single sequence that readily folds into the one or more structural targets that are given as input.
This program expects on standard input a file with one or more structures and, possibly, additional sequence constraints. It will then run a Markov chain to find a sequence that is optimal with regard to the structural targets and the user-defineable optimization function.
The user can give different optimization criteria on the command line, akin to a simple calculator.
If you find this program useful, please cite:
Christian Hoener zu Siederdissen, Stefan Hammer, Ingrid Abfalter, Ivo L. Hofacker, Christoph Flamm, Peter F. Stadler
Computational design of RNAs with complex energy landscapes
Biopolymers, 99, 12, 1124-1136, 2013, Wiley
- Author
- Christian Hoener zu Siederdissen
- Bug reports
- n/a
- Category
- Bioinformatics
- Copyright
- n/a
- Homepage
- n/a
- Maintainer
- choener@tbi.univie.ac.at
- Package URL
- n/a
- Stability
- experimental